February 19, 2026 | MB Daily News | Los Angeles CA

Eric Dane, ‘Grey’s Anatomy’ Star and ALS Awareness Advocate, Dies at 53

Eric Dane, best known for his role on Grey’s Anatomy, has died at the age of 53. He had been living with amyotrophic lateral sclerosis (ALS), a progressive neurological disease. His death has prompted tributes from fans, actors, and health advocates across the country.

Although many remember him as the charismatic Dr. Mark Sloan, Dane’s career extended far beyond one role. Over the years, he built a reputation as a versatile and dedicated performer. At the same time, he quietly faced personal and medical challenges.

From “McSteamy” to respected television actor

Eric Dane rose to fame in 2006 when he joined Grey’s Anatomy. His character, nicknamed “McSteamy,” quickly became a fan favorite. As a result, Dane became one of the show’s most recognizable stars.

However, he did not allow himself to be defined by a single role. After leaving the series, he starred in The Last Ship, where he played a Navy captain. Later, he took on a darker and more dramatic role in HBO’s Euphoria. These performances showed his range and depth as an actor.

In addition to television, Dane appeared in films such as Valentine’s Day and Burlesque. Therefore, his body of work reflected both commercial success and artistic growth.

Eric Dane’s battle with ALS

In recent years, Eric Dane publicly revealed his ALS diagnosis. ALS, also known as Lou Gehrig’s disease, affects nerve cells that control muscle movement. Over time, patients experience weakness and loss of mobility.

Despite the devastating diagnosis, Dane chose to speak openly about the disease. Instead of stepping away from public life, he became an advocate. He used interviews and public appearances to raise awareness. Moreover, he encouraged funding for medical research and patient support.

As the disease progressed, daily life became more challenging. Nevertheless, Dane remained focused on his family and meaningful work. Friends described him as resilient and determined. Consequently, many admired not only his acting but also his courage.

Advocacy and lasting impact

Eric Dane’s ALS advocacy became an important part of his legacy. For example, he highlighted the emotional and financial strain the disease places on families. Furthermore, he called for faster treatment development and expanded clinical access.

Because of his visibility, more people began talking about ALS. In turn, advocacy groups reported renewed interest and support. Although no cure currently exists, awareness remains a critical step toward progress.

A legacy beyond the screen

Eric Dane will be remembered for his talent, determination, and compassion. While his role on Grey’s Anatomy defined an era of television, his advocacy defined his final chapter.

Ultimately, his willingness to share his struggle gave hope and strength to others facing ALS. He is survived by his family, who have requested privacy during this difficult time.

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